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107-07-3

107-07-3
Cas No.:107-07-3
Appearance:Colorless liquid
Molecular Formula:C2H5ClO
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Detailed information

(Cas No 107-07-3) Chemistry
Formula                                                  C2H5ClO
Molecular weight                                      80.52
CAS No                                                   107-07-3
Appearance                                               Colorless liquid
Assay (GC, area%)                                     ≥ 99%
Acid value(Calculation based HCl)                 ≤ 0.05%
Water (according to Karl Fischer)                 ≤ 0.10%
Density (at 20°C, g/ml)                                1.200 - 1.203
(Cas No 107-07-3) Uses
(Cas No 107-07-3) is a building block in the production of pharmaceuticals, biocides and plasticizers. It is also used for manufacture of thiodiglycol. It is a solvent for cellulose acetate and ethyl cellulose, textile printing dyes, extraction of pine lignin, in dewaxing, refining of rosin, and the cleaning of machines.

Several dyes are prepared by the alkylation of aniline derivatives with chloroethanol.

Breathing (Cas No 107-07-3) can irritate the nose and throat causing coughing and wheezing.

Breathing (Cas No 107-07-3) can irritate the lungs causing coughing and/or shortness of breath.  Higher exposures may cause a build-up of fluid in the lungs

(pulmonary edema), a medical emergency, with severe shortness of breath.

(Cas No 107-07-3) can cause nausea. vomiting and abdominal pain.

(Cas No 107-07-3) can affect concentration and memory  and  can  cause  headache.  dizziness.lightheadedness. confusion, seizures (fits) and passing out.Higher levels can cause coma and even death.

(Cas No 107-07-3) Production
(Cas No 107-07-3) is produced by treating ethylene with hypochlorous acid:
CH2=CH2 + HOCl → HOCH2CH2Cl
(Cas No 107-07-3) Toxicity Data With Reference
1.  skn-rbt 200 mg/2H MLD
   TXAPA9    Toxicology and Applied Pharmacology. 16 (1970),382.
2.  eye-rbt 2 mg SEV
   AJOPAA    American Journal of Ophthalmology. 29 (1946),1363.
3.  eye-rbt 33 mg MOD
   TXAPA9    Toxicology and Applied Pharmacology. 16 (1970),382.
4.  eye-rbt 9 mg/6H MOD
   BUYRAI    Bulletin of Parenteral Drug Association. 31 (1977),25.
5.  sln-asn 74,500 μmol/L
   MUREAV    Mutation Research. 138 (1984),33.
6.  oms-rat:lvr 12 g/L
   JACTDZ    Journal of the American College of Toxicology. 1 (3)(1982),37.
7.  ihl-man LCLo:305 ppm/2H
   JIHTAB    Journal of Industrial Hygiene and Toxicology. 26 (1944),277.
8.  orl-rat LD50:71 mg/kg
   HYSAAV    Hygiene and Sanitation: English Translation of Gigiena Sanitariya. 36 (1971),376.
9.  ihl-rat LC50:290 mg/m3
   HYSAAV    Hygiene and Sanitation: English Translation of Gigiena Sanitariya. 26 (1971),376.
10.  ipr-rat LD50:58 mg/kg
   TXAPA9    Toxicology and Applied Pharmacology. 21 (1972),454.
RTECS :KK0875000
(Cas No 107-07-3) is toxic with an LD50 of 89 mg/kg in rats.
(Cas No 107-07-3) Consensus Reports
NTP Carcinogenesis Studies (dermal); No Evidence: mouse, rat NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-275 ,1985. ; Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program. EPA Extremely Hazardous Substances List.
(Cas No 107-07-3) Safety Profile
A poison by ingestion, inhalation, skin contact, intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic to humans by inhalation. It can affect the nervous system, liver, spleen, and lungs. An experimental teratogen. Mutation data reported. A severe eye and mild skin irritant. Flammable liquid when exposed to heat, flame, or oxidizers. To fight fire, use alcohol foam, CO2, dry chemical. Violent reaction with chlorosulfonic acid, ethylene diamine, sodium hydroxide. Reacts with water or steam to produce toxic and corrosive fumes. Potentially violent reaction with oxidizing materials. When heated to decomposition it emits highly toxic fumes of Cl? and phosgene. See also CHLORINATED HYDROCARBONS, ALIPHATIC.
Like most organochlorine compounds, (Cas No 107-07-3) combusts to yield hydrogen chloride and phosgene.
Hazard Codes:  T+,T,F 
Risk Statements : 26/27/28-39/23/24/25-11 
Safety Statements : 28-45-7/9-28A-36/37-16
RIDADR  :UN 1135 6.1/PG 1
WGK Germany  3
(Cas No 107-07-3) Standards and Recommendations
OSHA PEL: CL 1 ppm (skin)
ACGIH TLV: CL 1 ppm (skin); Not Classifiable as a Human Carcinogen
DFG MAK: 1 ppm (3.3 mg/m2)

DOT Classification:  6.1; Label: Poison

(Cas No 107-07-3) Analytical Methods

For occupational chemical analysis use NIOSH: (Cas No 107-07-3), 2513.
(Cas No 107-07-3) Specification

Other names of (Cas No 107-07-3) :2-chloroethyl alcohol, (Cas No 107-07-3), 2-chloro-1-ethanol, 2-monochloroethanol,glycol chlorohydrin,  2-hydroxyethyl chloride,  β-hydroxyethyl chloride, β-chloroethanol,chloroethanol,ethylchlorhydrin,  δ-chloroethanol, (Cas No 107-07-3), glycol monochlorohydrin.

(Cas No 107-07-3) Chronic Health Effects

The following chronic (long-term) health effects can occur at some time after exposure to (Cas No 107-07-3) and can last for months or years:

(Cas No 107-07-3) Cancer Hazard

There is no evidence that (Cas No 107-07-3) causes cancer in animals.  This is based on test results presently available to the New Jersey Department of Health and Senior Services from published studies.

(Cas No 107-07-3) Reproductive Hazard

(Cas No 107-07-3) may cause reproductive damage Handle with extreme caution.

(Cas No 107-07-3) Other Long-Term Effects

(Cas No 107-07-3) can irritate the lungs.  Repeated exposure may cause bronchitis to develop with cough,phlegm, and/or shortness of breath.

High or repeated exposure can damage the nerves causing weakness, "pins and needles." and poor coordination in arms and legs.

(Cas No 107-07-3) can cause liver and kidney damage.

(Cas No 107-07-3) Mixed Exposures

Because more than light alcohol consumption can cause liver damage, drinking alcohol can increase the liver damage caused by (Cas No 107-07-3).

the following control is recommended to (Cas No 107-07-3) 

   where possible, automatically pump liquid (Cas No 107-07-3)  from drums or other storage containers to process containers.good work practices can help to reduce hazardous

exposures.  

the following work practices are recommended to (Cas No 107-07-3)

   workers whose clothing has been contaminated by (Cas No 107-07-3)  should change into clean clothing promptly.

   contaminated work clothes should be laundered by individuals who have been informed of the hazards of exposure to (Cas No 107-07-3) .

   eye wash fountains should be provided in the immediate work area for emergency use.

   if there is the possibility of skin exposure, emergency shower facilities should be provided.

   on  skin  contact  with  ethylene  (Cas No 107-07-3) ,immediately wash or shower to remove the chemical. at the end of the workshift, wash any areas of the body that may have contacted (Cas No 107-07-3) , whether or not known skin contact has occurred. 

   do not eat.  smoke. or drink where (Cas No 107-07-3)  is handled, processed. or stored, since the chemical can be swallowed. wash hands carefully before eating, drinking, smoking, or using the toilet.

(Cas No 107-07-3)  handling and storage

   prior to working with (Cas No 107-07-3)  you should be trained on its proper handling and storage.

ethylene  (Cas No 107-07-3)   reacts  violently  with chlorosulfonic acid; ethylene diamine;sodium hydroxide and oxidizing agents(such    as    perchlorates.    peroxides,permanganates.   chlorates.   nitrates,chlorine. bromine and fluorine).

(Cas No 107-07-3)  is not compatible with strong bases (such as potassium hydroxide); strong acids (such as hydrochloric, sulfuric and nitric); and alkaline metals.

store in tightly closed containers in a cool. well-ventilated area away from water and steam as corrosive gases are produced.

sources of ignition. such as smoking and open flames, are prohibited where (Cas No 107-07-3)  is used, handled. or stored in a manner that could create a potential fire or explosion hazard.

(CAS No:107-07-3)  images

107-07-3107-07-3107-07-3107-07-3107-07-3107-07-3107-07-3107-07-3

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