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Cas No.:107-07-3
Appearance:Colorless liquid
Molecular Formula:C2H5ClO

Detailed information

(EC No 203-459-7) Chemistry

Formula                                                      C2H5ClO

Molecular weight                                         80.52

CAS No                                                     107-07-3

Appearance                                                 Colorless liquid
Assay (GC, area%)                                       ≥ 99%

Acid value(Calculation based HCl)                ≤ 0.05%

Water (according to Karl Fischer)                 ≤ 0.10%

Density (at 20°C, g/ml)                                 1.200 - 1.203

(EC No 203-459-7) Uses
(EC No 203-459-7) is a building block in the production of pharmaceuticals, biocides and plasticizers. It is also used for manufacture of thiodiglycol. It is a solvent for cellulose acetate and ethyl cellulose, textile printing dyes, extraction of pine lignin, in dewaxing, refining of rosin, and the cleaning of machines.
Several dyes are prepared by the alkylation of aniline derivatives with chloroethanol.

(EC No 203-459-7) Production
(EC No 203-459-7) is produced by treating ethylene with hypochlorous acid:

(EC No 203-459-7) Toxicity Data With Reference
1.  skn-rbt 200 mg/2H MLD
   TXAPA9    Toxicology and Applied Pharmacology. 16 (1970),382.
2.  eye-rbt 2 mg SEV
   AJOPAA    American Journal of Ophthalmology. 29 (1946),1363.
3.  eye-rbt 33 mg MOD
   TXAPA9    Toxicology and Applied Pharmacology. 16 (1970),382.
4.  eye-rbt 9 mg/6H MOD
   BUYRAI    Bulletin of Parenteral Drug Association. 31 (1977),25.
5.  sln-asn 74,500 μmol/L
   MUREAV    Mutation Research. 138 (1984),33.
6.  oms-rat:lvr 12 g/L
   JACTDZ    Journal of the American College of Toxicology. 1 (3)(1982),37.
7.  ihl-man LCLo:305 ppm/2H
   JIHTAB    Journal of Industrial Hygiene and Toxicology. 26 (1944),277.
8.  orl-rat LD50:71 mg/kg
   HYSAAV    Hygiene and Sanitation: English Translation of Gigiena Sanitariya. 36 (1971),376.
9.  ihl-rat LC50:290 mg/m3
   HYSAAV    Hygiene and Sanitation: English Translation of Gigiena Sanitariya. 26 (1971),376.
10.  ipr-rat LD50:58 mg/kg
   TXAPA9    Toxicology and Applied Pharmacology. 21 (1972),454.
RTECS :KK0875000
(EC No 203-459-7) is toxic with an LD50 of 89 mg/kg in rats.

(EC No 203-459-7) Consensus Reports
NTP Carcinogenesis Studies (dermal); No Evidence: mouse, rat NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-275 ,1985. ; Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program. EPA Extremely Hazardous Substances List.

(EC No 203-459-7) Safety Profile
A poison by ingestion, inhalation, skin contact, intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic to humans by inhalation. It can affect the nervous system, liver, spleen, and lungs. An experimental teratogen. Mutation data reported. A severe eye and mild skin irritant. Flammable liquid when exposed to heat, flame, or oxidizers. To fight fire, use alcohol foam, CO2, dry chemical. Violent reaction with chlorosulfonic acid, ethylene diamine, sodium hydroxide. Reacts with water or steam to produce toxic and corrosive fumes. Potentially violent reaction with oxidizing materials. When heated to decomposition it emits highly toxic fumes of Cl? and phosgene. See also CHLORINATED HYDROCARBONS, ALIPHATIC.

Like most organochlorine compounds, (EC No 203-459-7) combusts to yield hydrogen chloride and phosgene.
Hazard Codes:  T+,T,F 
Risk Statements : 26/27/28-39/23/24/25-11 
Safety Statements : 28-45-7/9-28A-36/37-16
RIDADR  :UN 1135 6.1/PG 1
WGK Germany  3

(EC No 203-459-7) Standards and Recommendations
OSHA PEL: CL 1 ppm (skin)
ACGIH TLV: CL 1 ppm (skin); Not Classifiable as a Human Carcinogen
DFG MAK: 1 ppm (3.3 mg/m2)
DOT Classification:  6.1; Label: Poison
(EC No 203-459-7) Analytical Methods
For occupational chemical analysis use NIOSH: (EC No 203-459-7), 2513.

(EC No 203-459-7) Specification

Other names of (EC No 203-459-7) :2-chloroethyl alcohol, (EC No 203-459-7), 2-chloro-1-ethanol, 2-monochloroethanol,glycol chlorohydrin,  2-hydroxyethyl chloride,  β-hydroxyethyl chloride, β-chloroethanol,chloroethanol,ethylchlorhydrin,  δ-chloroethanol, (EC No 203-459-7), glycol monochlorohydrin.


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