Published reports on ethylene chlorohydrin

Ethylene chlorohydrin formation in radiation- and ethylene oxide-sterilized poly(vinyl chloride)

ABSTRACT Published reports on the formation of ethylene chlorohydrin in ethylene oxide-sterilized poly(vinyl chloride) are contradictory. The present paper discusses parameters involved in the ethylene chlorohydrin formation, such as the stabilizer system, plasticizer content and thermal strain during manufacture. It is shown that ethylene chlorohydrin can be formed in ethylene oxide-sterilized poly(vinyl chloride) previously sterilized by irradiation, in amounts dramatically exceeding published 'safe levels'

Determination of ethylene oxide, ethylene chlorohydrin, and ethylene glycol in aqueous solutions and ethylene oxide residues in associated plastics

Abstract A gas chromatographic (GC) method was developed for the determination of ethylene oxide and its two reaction products, ethylene chlorohydrin and ethylene glycol, in aqueous ophthalmic solutions. Propylene oxide was used as an internal standard. All three components were determined in one isothermal chromatographic analysis in <15 min. An extraction method for the determination of ethylene oxide residues in plastic components was also developed, and certain plastics with different ethylene oxide retention characteristics were identified.